COI by Condition

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All Diseases

  • Research Triangle Institute. Cost-of-Illness Summaries for Selected Conditions. (January 2006). (pdf). This is a tabular compilation of COI estimates for a large number of diseases, based on the studies reviewed in the report below, updated to 2004 dollars, with a breakdown of direct, indirect and intangible losses, along with other selected details about characteristics of each study.
  • Research Triangle Institute. Reviews of Current Cost-of-Illness Studies. (January 2006). (pdf). This is a 300+ page compilation of abstracted COI studies using a common template for reporting on methods and sources. The compilation is intended to update the NIH 2000 report and excludes all studies from that report except in instances where no more recent study could be found for a particular disease.
  • Dorothy P. Rice, Thomas A. Hodgson and Andrea N. Kopstein. “The Economic Costs of Illness: A Replication and Update.” Health Care Financing Review 7, No. 1 (Fall 1985): 61-80.
  • “The Relation Between Funding by the National Institutes of Health and the Burden of Disease” (New England Journal of Medicine, 6/17/99)

Broad Condition Categories

Injuries

  • Dorothy P. Rice, E.J. McKenzie and Associates.  Cost of Injury in the United States: A Report to Congress.  San Francisco and Baltimore Injury Prevention Center, Johns Hopkins University, 1989, cited in Jeffrey W. Runge. “The Cost of Injury” Emergency Medicine Clinics of North America 11, No. 1 (February 1993): 241-253.

Mental Illness

  • Facts and Economic Costs (National Mental Health Association)
  • Dorothy P. Rice, Sander Kelman, Leonard S. Miller, Sarah Dunmeyer. The Economic Costs of Alcohol and Drug Abuse and Mental Illness: 1985. Report submitted to Office of Financing and Coverage Policy of the Alcohol, Drug Abuse, and Mental Health Administration, U.S. Department of Health and Human Services. San Francisco: Institute for Health and Aging, University of California, 1990.

Musculoskeletal Conditions

  • A. Praemer, S. Furner, and D.P. Rice.  Section 5: “Costs of Musculoskeletal Conditions.”  Musculoskeletal Conditions in the United States.  American Academyof Orthopaedic Surgeons, 1992.

Senile Dementia

  • Lien-Fu Huang, William S. Cartwright, and Teh-Wei Hu. “The Economic Cost of Senile Dementia in the United Sates, 1985” Public Health Reports 103, No. 1 (January-February 1988): 3-7.

Violent Crime (rape, robbery, assault, arson and murder)

  • Violence Costs (Pacific Center for Violence Prevention)
  • Ted R. Miller, M.A. Cohen and S. B. Rossman, Victim Costs of Violent Crime and Resulting Injuries.  Health Affairs 12(4): 195-197.

Adverse Events

  • Eric J Thomas; David M Studdert; Joseph P Newhouse; Brett I W Zbar; et al. Costs of medical injuries in Utah and Colorado. Inquiry Fall 1999; 36 (3): 255-264.

Specific Illnesses/Conditions

Figures in parentheses show approximate ranking of illnesses according to annual costs in the U.S. as of 2000, based on unpublished estimates by Christopher J. Conover. See Annual Cost of Illness and Injury, Most Costly Health Conditions in U.S. (2000).

AIDS (#1)

  • Fred Hellinger. “Forecasts of the Costs of Medical Care for Persons with HIV: 1992-1995.” Inquiry (Fall, 1992).
  • Mark S. Thompson and Heidi J. Meyer, “The Cost of AIDS: Alternative Methodological Approaches,” in Lee Sechrest, Howard Freeman and Albert Mulley, eds., Health Services Research Methodology: A Focus on AIDS.  National Center for Health Services Research and Health Care Technology Assessment,September 1989: 95-106.

Alcoholism (#2)

  • Dorothy P. Rice, Sander Kelman, Leonard S. Miller, Sarah Dunmeyer. The Economic Costs of Alcohol and Drug Abuse and Mental Illness: 1985. Report submitted to Office of Financing and Coverage Policy of the Alcohol, Drug Abuse, and Mental Health Administration, U.S. Department of Health and Human Services. San Francisco: Institute for Health and Aging, University of California, 1990.

Alzheimer’s (#3)

  • Richard L. Ernst and Joel W. Hay. “The US Economic and Social Costs of Alzheimer’s Disease Revisited.” American Journal of Public Health 84, No. 8 (August 1994): 1261-1264.

Arthritis (#4)

  • A. Praemer, S. Furner, and D.P. Rice.  Section 5: “Costs of Musculoskeletal Conditions.”  Musculoskeletal Conditions in the United States.  American Academy of Orthopaedic Surgeons, 1992.

Cancer, Reproductive (#11)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Cancer, Respiratory (#14)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Coronary Insufficiency (#20)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Coronary Sudden Death (#18)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Coronary Disease, All Other MI (#9)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Depression (#7)

  • Paul E. Greenberg, Laura E. Stiglin, Stan N. Finkelstein and Ernst R. Berndt. “The Economic Burden of Depression in 1990” Journal of Clinical Psychology 54:11 (November 1993): 405-426.

Diabetes (#12)

  • “The Economic Costs of Non-Insulin-Dependent Diabetes Mellitus” Journal of the American Medical Association 262, No. 19 (November 17, 1989): 2708-2713.
  • Thomas J Songer, Lorraine Ettaro, and the Economics of Diabetes Project Pane. Studies on the Cost of Diabetes (1998). Summarizes the results of the direct costs of diabetes from 19 cost estimates for the years 1969-1997, adjusted to 1997 dollars using alternative price adjusters and accounting for rising diabetes prevalence during this period. This analysis shows a 6.5-fold difference in the 1997 medical-price-adjusted estimates for a single disease across studies that vary in the methods and sources of data used to calculate COI for diabetes.

Drug Abuse (#16)

  • Dorothy P. Rice, Sander Kelman, Leonard S. Miller, Sarah Dunmeyer. The Economic Costs of Alcohol and Drug Abuse and Mental Illness: 1985. Report submitted to Office of Financing and Coverage Policy of the Alcohol, Drug Abuse, and Mental Health Administration, U.S. Department of Health and Human Services. San Francisco:Institute for Health and Aging, University of California, 1990.

Falls (#5)

  • Dorothy P. Rice, E.J. McKenzie and Associates.  Cost of Injury in the United States: A Report to Congress.  San Francisco and Baltimore Injury Prevention Center, Johns Hopkins University, 1989, cited in Jeffrey W. Runge. “The Cost of Injury” Emergency Medicine Clinics of North America 11, No. 1 (February 1993): 241-253.

Firearm Injuries (criminal and accidental)  (#13)

  • Wendy Max and Dorothy P. Rice. “Shooting in the Dark: Estimating the Cost of Firearm Injuries” Health Affairs 12, No. 4 (Winter 1993): 171-185.

Fractures, Hip (#19)

  • A. Praemer, S. Furner, and D.P. Rice.  Section 5: “Costs of Musculoskeletal Conditions.”  Musculoskeletal Conditions in the United States.  American Academy of Orthopaedic Surgeons, 1992.

Fractures, Non-hip (#17)

  • A. Praemer, S. Furner, and D.P. Rice.  Section 5: “Costs of Musculoskeletal Conditions.”  Musculoskeletal Conditions in the United States. American Academy of Orthopaedic Surgeons, 1992.

Migraine Headaches (#23)

  • Gregory de Lissovoy and Stephanie S. Lazarus. “The Economic Cost of Migraine: Present State of Knowledge.” Neurology 44 (Suppl 4) June 1994: S56-S62.

Motor Vehicle Accidents (#6)

  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Multiple Sclerosis (#22)

  • Kathryn Whetten-Goldstein, Frank A. Sloan, Larry B. Goldstein, Elizabeth D. Kulas. “A Comprehensive Assessment of the Cost of Multiple Sclerosis in the United States.” Multiple Sclerosis 4 (3) (1998).

Obsessive-Compulsive Disorder (#21)

  • Robert L. DuPont et al. Medical Interface. April 1995, cited in Medical Benefits June 15, 1995, p. 5.

Schizophrenia (#10)

  • Dorothy P. Rice and L.S. Miller “The Economic Burden of Schizophrenia” Paper presented at the Sixth Biennial Research Conference on the Economics of Mental Health, Bethesda, MD, September 21-22, 1992, pp 1-17, cited in Agnes Rupp and Samuel J. Keith, “The Costs of Schizophrenia: Assessing the Burden.” Psychiatric Clinics ofNorth America 16, No. 2 (June 1993): 413-423. Daniel M. Huse, Gerry Oster, Alice R. Killen, Michael J. Lacey, Graham A. Colditz.

Stroke (#8)

  • David Matchar, The Cost of Stroke in the U.S.: National Stroke Association Press Conference, May 1994.
  • Mark S. Adelman.  National Survey of Stroke, Chapter 6: Economic Impact.  Stroke 12, Supplement 1, March-April 1981: 69-87.
  • Nelson S. Hartunian, Charles N. Smart, Mark S. Thompson. “The Incidence and Economic Costs of Cancer, Motor Vehicle Injuries, Coronary Heart Disease, and Stroke: A Comparative Analysis” American Journal of Public Health 70, No. 12 (December 1980): 1249-1260.

Urinary Incontinence (65+) (#15)

  • Teh-wei Hu. “The Economic Impact of Urinary Incontinence.” Clinics in Geriatric Medicine 2, No. 4 (November 1986): 673-687.

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